Welcome to the MacIntosh Lab
Our laboratory is interested in two different areas of research:
Part of the laboratory studies the interaction
between plants and insects. In particular, we study how plants respond to insect attacks, and the mechanisms used by insects
to avoid plant defenses and to take over plant metabolism.
We are also interested in the biological role of ribonucleases associated
with the secretory pathway, in particular members of the RNase T2 family. We have described their housekeeping role in rRNA
decay, and other functions related to plant defense
Our current projects are:
- Characterization of the transcriptional and metabolic changes induced in soybean by the soybean aphid,
- Role of general stress responses in the interaction between plants and aphids.
- Identification of novel signaling
pathways that control defense responses to insects and mechanical wounding in Arabidopsis and soybean.
- Role of RNase T2 enzymes
in rRNA decay and the link between RNA decay and autophagy.
- Evolution of the RNase T2 family
>Melissa Hilwig is now an Assistant Professor at Robert Morris University
>Matthew Studham joined the laboratory of Dr. Erik Sonnhammer at Stockholm University, Sweden, as a postdoc
>Mariana Chiozza is now working as Breeder Jr in the Instituto de Agrobiotecnología Rosario (INDEAR), Argentina
Department of Biochemistry, Biophysics and Molecular Biology
Iowa State University
Thanks to our funding sources: